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Early or late baseline?

by: Nobel Biocare News

Not all study protocols are the same.

Early or Late Baseline?

At the 25th Anniversary Meeting of the Academy of Osseointegration, an international group of Nobel Biocare researchers presented the results of a literature review that applied strict inclusion criteria comparing the preferred study protocols of three major implant manufacturers – Astra Tech, Nobel Biocare, and Straumann.

The study also compared the baseline chosen for radiographic evaluation when assessing marginal bone level change.

Different use of protocols

Covering clinical articles published in peer-reviewed journals over a span of more than 14 years, the review demonstrates noteworthy differences in the types of surgical and loading protocols followed in these articles. While the vast majority of the “study groups” reviewed in the articles on Nobel Biocare implants have followed a one-stage surgical protocol, for instance, almost three out of four featuring Astra Tech implants report on a two-stage protocol instead.

As far as loading protocols are concerned, immediate loading cases were relatively underrepresented in articles written about both Astra Tech and Straumann implants. In the material under review, significant differences were also seen between the points-in-time at which a radiographic baseline was established for the assessment of marginal bone level change. 

Since a relatively late baseline misses the pronounced initial marginal bone remodeling typical after implant insertion, the choice of different time-points makes it very difficult to compare results between articles.

In summary, the review showed that the study groups in which Nobel Biocare implants had been used reported the highest percentage (84%) of one-stage protocols and the highest percentage (45%) of immediate loading protocols; and that they began measuring marginal bone re-modeling most frequently (79%) at implant insertion.

More to explore:

Please click here for more information about “Comparison of Radiographic Baselines and Loading Protocols Utilized in Implant-studies”.