Media & news

Report on new membrane

by: Ruth Bloechlinger

In a comparative study, creos xenoprotect monolayer non-cross-linked collagen membrane shows higher tensile strength in vitro and greater vascularization in vivo.¹

Report on a new membrane

In vitro, the creos xenoprotect (Nobel Biocare / Remaix, Matricel) showed significantly greater tensile strength in terms of both force at break (N) and stress at break (N/mm²) and in terms of suture retention when compared to a bi-layer non-cross-linked collagen membrane (Bio-Gide, Geistlich).

An accompanying animal study confirmed slower biodegradation of creos xenoprotect. Degradation was similar between the two membranes during the first nine weeks, but a marked difference at 20 weeks showed only a slight decrease in thickness of the creos xenoprotect membrane compared to 51% loss of thickness of the comparison membrane.

Histomorphometric analyses at 20 weeks showed higher vascularization of the creos xenoprotect membrane with approximately two-fold increase in the number of blood vessels at week 20.

More to explore:

Please click here to read the abstract of the study.

To learn more about creos xenoprotect, please click here.

Looking to add to your skill set? Check out Nobel Biocare's global course catalog to find a training program near you.


Bozkurt A, Apel C, Sellhaus B, van Neerven S, Wessing B, Hilgers RD, Pallua N. COIR 2013 [epub 28 October] DOI: 10.1111/clr.12284.